Magnolia Officinalis P. E. Magnolol & Honokiol Herbal Extract

• Certification: ISO
• Assay Method: HPLC
• Application Form: Tablet, Capsule, Cream
• Application: Food, Health Care Products, Medicine, Cleaning Products, Cosmetics, Cosmetic Products
• State: Powder
• Extract Source: Magnolia Bark
• Model NO.: Magnolia officinalis P. E.
• Product Name: Magnolia Officinalis P. E.
• Active Ingredient: Magnolol & Honokiol
• Extraction Type: Supercritical CO2
• Grade: Pharmaceutical Grade
• Function: Anti - Bacterial, Anti - Inflammatory, Whitening
• Solvent Residue: Solvent-Free Residue
• Storage Conditions: Store in a Cool Place Away From Light
• Shelf Life: 2 Years
• Transport Package: 1.1 Kg Aluminum Foil Bag; 2.10 Kg Carton Packagi
• Specification: 98%
• Trademark: HONGKANGBIO
• Origin: China
• HS Code: 2907299090
• Production Capacity: 10000kg/M

Product Description

Magnolia officinalis P. E. Magnolol & Honokiol Herbal Extract

Product Name	Honokiol
CAS No	35354-74-6
Specification	98%
Test Method	HPLC
Appearance	White powder
Grade	Cosmetic grade

Magnolol + Honokiol

Magnolol and honokiol are the two main active ingredients of traditional Chinese medicine Magnolia, and have
a wide range of pharmacological effects such as antibacterial, anti-inflammatory, anti-tumor muscle
relaxation,cholesterol reduction and anti-aging. As early as 1930, Japan's Sugiyra first isolated magnolol
from the bark of Chinese magnolia, and proved that this ingredient is also contained in Japanese magnolia, but
the amount is very low. In 1973, Fujita successively isolated magnolol and its isomers and magnolol from
Japanese Magnolia and Magnolia.

Our magnolo advantages:

Shaanxi Hongkang Biological Technology Co., Ltd is the most professional manufacturer of

Magnolol and Honokiol.

Why do we use Supercritical CO2 Fluid Extraction?

1-The operation is close to room temperature (34 ~ 39 °C) , and the whole extraction process is covered with
CO2 gas, which effectively prevents the oxidation and degradation of heat-sensitive materials. It can completely
retain the biological activity, and can extract the substance with high boiling point, low volatility and pyrolytic at
the temperature far below its boiling point.

2- Supercritical co2 Fluid Extraction is the most environmentally friendly extraction method, the whole process
does not contain organic solvents, so the extract without residual solvents, thus preventing the extraction process
of human harmful substances and pollution of the environment, to ensure 100% of the natural.

3-Supercritical co2 Fluid Extraction also has the function of anti-oxidation and sterilization, which is beneficial
to guarantee and improve the quality of products.

Our Product Characteristics

1.Natural Chinese herb plant extract, high safety.

2.White crystalline powder, light and characteristic smell.

3.High content of active component.

4.Small molecular weight, can be used as a pilot drug to exert utility.

5.High efficiency and broad spectrum of antibacterial property.

6.Good dispersity and solubility. Stable properties under heat, acid and alkali condition.

7.High safety, no organic solvent residual,have no heavy metal residual.

Function of Honokiol

Effects on the digestive system

        The extract of magnolia officinalis officinalis could inhibit the formation of salt-acid ulcer in mice. Honokiol,
the active ingredient of Magnolol, can inhibit gastric acid secretion and resist ulcer. Magnolol can obviously fight
diarrhea in sensene-leaved mice and promote bile flow in rats, indicating that Magnolol can promote digestive
system as well as wenli medicine. Magnolia officinalis treating food, cold and damp dysentery, temperature in pain.
 
Analgesic and anti-inflammatory pharmacological effects
      Magnolia officinalis is an aromatic and wet herb with analgesic and anti-inflammatory activities. Magnolia
officinalis ethanol extract 5g/kg and 15g/kg have significant analgesic effects, significantly reduce the increase
of capillary permeability in the abdominal cavity of mice caused by acetic acid, and significantly inhibit the ear
swelling of mice caused by xylene and the paw swelling of mice caused by carrageenin. The experiment shows
that magnolia officinalis has obvious anti-inflammatory and analgesic effects.


Central and peripheral muscle relaxation and antispasmodic effect
      Magnolia officinalis is often used for extreme nervous, excited state and cause unknown vibration.
Magnolol, the extract of magnolia officinalis, has the effect of blocking neuromuscular junction and can induce
the central muscle relaxation similar to that of myophenol. And honokiol have sedative and anti-anxiety effects.
At ultra-high doses, beta eucalyptus alcohol and diphenyl ethyl ureide sodium showed stronger effects in
preventing electroconvulsive seizures. It is expected that beta eucalyptus alcohol can be used as a synergistic
therapy in antiepileptic therapy or antiepileptic therapy with diphenyl ethyl ureide sodium.

Application of Honokiol

(1).Pharmaceutical hygiene products and antimicrobial agents
Magnolol Honokiol, the active component of magnolia officinalis extract, can be used as an antibacterial agent
(gram-negative bacteria and acid-resistant bacteria) and can be used to prevent and treat acne. 
 

(2).Daily chemical wash and care application
Oral hygiene products to fight tooth decay, inhibit tooth decay. The inhibition of Magnolol Honokiol on NF-cB
cells proved to improve the function of skin immune cells and had anti-inflammatory effect.

(3)Cosmetic applications
The inhibition of Magnolol Honokiol on NF-cB cells proved to improve the function of skin immune cells and had
anti-inflammatory effect. Magnolol Honokiol can also be used as an antioxidant and skin whitening agent.

Shaanxi Hongkang Biological Technology Co., Ltd was founded in 2010, professional committed to the
natural plant active ingredient research, development, production and sales, with own import and export rights.
Widely used in cosmetics, health products, food additives and other industries. Shaanxi Hongkang will
continuously to focus on and serve human health from a global perspective, and create high-quality products
in the field of green health.

After years of continuous development, company has been accumulated rich experience in international trade
and customer resources, established a stable customer base and perfect marketing service network.Company
has perfect quality assurance system, implement strict quality control standards.

The quality management department is equipped with a number of sets of UV, GC, HPLC, GC-MS and
other advanced testing and experimental instruments.Besides, it has a detailed division of labor for the
three functions of process research, quality assurance and quality inspection, which can effectively and
comprehensively control the quality of the production process, conduct comprehensive inspection and analysis
on the final product, and ensure the quality of the product.

Providing users with satisfactory products is our constant pursuit. the company has several plant extraction
production lines in the workshop,And supercritical CO₂  extraction,column separation technology,
membrane separation technology, high-efficiency counter current extraction, microwave drying
technology, spray drying and other advanced production equipment, and has formed an annual output
of 200 tons of high-purity plant extracts production capacity, Complete product specifications and stable quality.
With the certificate of ISO9001:14001:45001.

1. Can I get some free products for testing?
Sure, If you have a need for this,we can provide free samples after you pay for shipping.

2. What is the meaning of the minimum order quantity?
We have different minimum order metrics for different products, usually 1KG

3. How much time can your send the goods?
Usually 3-5 days,except statutory holidays

4. Is there any discount?
Of course, the price will vary with the quantity, the more you buy, the more discounts you have.

5. How do you deal with quality complaints?
We are striving to keep quality issues close to zero,If quality problems have occurred,we will make
a consistent replacement or refund for customers who have quality problems.