Angelica Dahurica Extract 1% 98% Imperatorin for Antibacterial Ammidin

• Certification: RoHS, BRC, ISO, FDA, HACCP
• Assay Method: HPLC
• Application Form: Tablet, Capsule
• Application: Health Care Products, Medicine, Cosmetic
• State: Powder
• Extract Source: Angelica Dahurica Extract
• Model NO.: 482-44-0
• CAS: 482-44-0
• Mf: C16h14o4
• Transport Package: 1.1 Kg Aluminum Foil Bag; 2.10 Kg Carton Packagi
• Specification: 1% 98%
• Trademark: HONGKANG
• Origin: China
• Production Capacity: 10000kg/M

Product Description

Product Name	Angelica dahurica Extract Imperatorin
Exterior	Brown powder(1%), write powder(98%)
Active Ingredient	Imperatorin 1% 98%
Test Method	HPLC
Extraction Solvent	Ethanol/ Water
CAS NO	482-44-0
Molecular Formula	C16H14O4
Molecular Weight	270.27996

The imperatorin extracted from the dried roots of the genus Umbelliferae has been shown to have antibacterial,
antiasthmatic, antiallergic, dilated blood vessels, and inhibition of tumor cell proliferation. Lipid microspheres
and liposomes are drug carriers prepared by using natural lipid materials such as phospholipids and cholesterol.
With this carrier, drugs can be transported to the site of the lesions, and the drug molecules can be protected
from degradation by biological enzymes. The pre-prescription study and drug stability test of imperatorin can
provide a theoretical basis for the design optimization of the injection of imperatorin microspheres. The application
of lipid microsphere technology to the study of imperatorin drugs can reduce the renal side effects of drugs under
the precursors that maintain efficacy.


Specifiaction:
Imperatorin : 1%, 98% by HPLC


Effect on the central nervous system

        The effect of imperatorin on seizures was studied using the maximal electroconvulsive epileptic seizure
threshold model in mice. The study found that intraperitoneal injection of 50 and 100 mg/kg-1 of imperatorin
30 minutes earlier could increase the voltage threshold of seizures in mice by 38% and 68%, respectively,
and demonstrated that imperatorin improves mice with electrical stimulation. The effect of the onset threshold
is dose and time dependent.
 
Effects on the cardiovascular system

      The chromatographic retention peaks of imperatorin and verapamil were similar. It can reduce the protein
content and cell volume of cardiomyocytes prestimulated by angiotensin I, and its effect is dose-dependent: the
ratio of heart weight of spontaneously hypertensive rats treated with angiotensin I is significantly reduced,
indicating that the effect of angiotensin I on both in vivo and in vitro is anti-hypertrophy.


Antibacterial and antiviral activity

      Imperatorin has significant antibacterial and antiviral activity. Seven components were extracted
from the flowers of Magydaris tomcntosa, and four components, including eucrutin, were tested for
bacteriostasis. It was found that eucrutin had strong inhibitory activity against both gram-positive
and gram-negative bacteria (minimum bacteriostasis concentration was 32-128 mg-ml).

Package:1kg/aluminum foil bag;25Kgs in fiber-drums with two-plastic bags inside

Net Weight:25kgs/Drum/Gross Weight:28kgs/Drum
Drum Size & Volume:I.D.42cm × H52cm,0.08 m³/Drum
Storage:Stored in dry and cool place,keep away from strong light and heat.
Shelf Life:Two years when properly stored.
Delivery Time:Around 3-5 workdays after your payment.