Pure Natural Cnidium Fruit Extract 10% 90% 98% Osthole Cosmetics Raw Material

• Customization: Available
• Certification: ISO, HACCP
• Assay Method: HPLC
• Model NO.: Osthole
• Application: Health Care Products, Medicine, Cosmetic Products
• State: Powder
• Extract Source: Cnidium Monnieri Extract
• Product Name: Cnidium Monnieri Extract
• Appearance: Brown Green Powder
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1 Kg
• CAS No: 484-12-8
• Sample: Available
• Mf: C15h16o3
• Model Number: 10%-98%
• Transport Package: 1.1 Kg Aluminum Foil Bag; 2.10 Kg Carton Packagin
• Specification: 10%/50%/90%/98%
• Trademark: HongKang
• Origin: China
• Production Capacity: 100000/Month

Product Description

Pure Natural Cnidium Fruit Extract 10% 90% 98% Osthole Cosmetics Raw Material

Product Name	Cnidium monnieri Extract Osthole
Exterior	White, light yellow, brownish yellow powder
Active Ingredient	Osthole 10%, 50%, 90%, 98%
Test Method	HPLC
Extraction Solvent	Ethanol
CAS NO	482-12-8
Molecular Formula	C15H16O3
Molecular Weight	244.29

What is it?Cnidium monnieri is annual herb,height 30-80cm. Cnidium monnieri leaf is alternate,compundumbel inflorescence.
Cremocarp, ellipsoidal, 2-4 mm long, about 2 mm in diameter. Externally greyish-yellow or greyish-brown; with
2outcurved stylopods at the summit, and sometimes with a fine fruit stalk at the base. Dorsal surface of mericarps
with five thin and longitudinal ridges, commissural surface flattened, with two brown and slightly raised longitudinal
ribs. Cnidium monnieri's pericarp lax and fragile, easily rubbed off, seed small, greyish-brown and oily. Odour,
aromatic; taste, pungent, cool and numb.

Specifiaction:
Osthol : 10%, 50%, 90% 98% by HPLC

Antiarrhythmic effect

        Water extract and total coumadin from fructus cnidium have obvious preventive effects on chloroform
induced ventricular fibrillation in mice and calcium chloride induced ventricular fibrillation in rats. Fructus
cnidium and zanthoxylum acetaminophen also have this pharmacological effect and can improve ventricular
electrofibrillation threshold in rabbits. The water extract, total coumarin, cnidium, and phenols of zanthoxylum
had significant inhibitory effects on the flow of sodium ions in the myocardial cell membrane.
 
Antihypertensive, inhibition of vascular dilatation

      Osthol had a dose-dependent negative inotropic effect on the left atrium of isolated guinea pigs and a negative
frequency effect on the left atrium of isolated guinea pigs. In addition to the polarization induced by norepinephrine,
CaCl2 and high K+, the aorta contraction dose-response curve of rabbits was shifted to the right and the maximum
response was decreased, indicating the role of biosynthetic compound in relaxing vascular smooth muscle. Fructus
cnidium has a certain antihypertensive effect.

Effects on respiratory system

    Cnidium monnieri total coumarin with relaxation by drugs (histamine and acetylcholine) caused by bronchial
spasms and diastole bronchus role directly, this function can be B - adrenaline receptor blockers block by propranolol,
mice after total coumarin cnidium monnieri, obviously increase the amount of phenol red drain in the body, shows
strong expectoranting action.

Anti-inflammatory effects

Cnidium cnidium and phenolic zanthoxylum could inhibit the ear shell swelling of mice caused by xylene and the
increase of capillary permeability in abdominal cavity caused by acetic acid. Osthol and acetonol had significant
inhibitory effects on foot swelling in rats and rats with bilateral adrenal resection. Osthol could also reduce the PGE
content in the inflammatory tissues of the swollen part of the foot in rats, but osthol did not affect the PGE content in
the inflammatory tissues of the swollen part of the foot in rats.

Effects on the nervous system
The total coumarin of cnidium cnidium has an inhibitory effect on central nervous system. Osthol can significantly
enhance the hypnotic effect of pentobarbital sodium on subthreshold hypnotic dose in mice, and this hypnotic effect
is dose-related. Cnidium cnidium can promote the learning and memory of mice, and significantly improve the memory
acquisition, consolidation and direction discrimination of mice.


Anti - mutagenesis, anti - cancer effect
Cnidium, parsley b, bergamot lactone, isorhein, zanthoxylum acetaminophen and zanthoxylum toxin have high activity
in inhibiting the mutagenesis of aflatoxin B1. Water extract of cnidium could inhibit S130 sarcoma, prolong survival days
and inhibit tumor growth.

Skin care products and cosmetics
It can inhibit the formation of various inflammatory factors and has a good therapeutic effect on facial acne and acne.
For allergic skin diseases, such as eczema, urticaria has a good effect, can be used in anti - allergic cosmetics.

Dermatological drugs

Osthole has antispasmodic, antihypertensive, antiarrhythmic, immune function and broad-spectrum antibacterial effects.
It has strong pharmacological activity and is an effective pharmaceutical ingredient that can be used in the pharmaceutical industry.

Pesticides and pesticides

 As a new type of biological pesticide, it can inhibit pests and plant pathogens. It is an effective botanical insecticide.

 

Shaanxi Hongkang Biological Technology Co., Ltd was founded in 2010, professional committed to the
natural plant active ingredient research, development, production and sales, with own import and export
rights.Widely used in cosmetics, health products, food additives and other industries. Shaanxi Hongkang
 will continuously to focus on and serve human health from a global perspective, and create high-quality
products in the field of green health.

After years of continuous development, company has been accumulated rich experience in international
 trade and customer resources, established a stable customer base and perfect marketing service network.
Company has perfect quality assurance system, implement strict quality control standards.

The quality management department is equipped with a number of sets of UV, GC,HPLC, GC-MS and other
advanced testing and experimental instruments.Besides, it has a detailed division of labor for the three functions
of process research, quality assurance and quality inspection, which can effectively and comprehensively control
the quality of the production process, conduct comprehensive inspection and analysis on the final product, and
ensure the quality of the product.

Providing users with satisfactory products is our constant pursuit. the company has several plant extraction
production lines in the workshop,And supercritical CO2 extraction,column separation technology, membrane
separation technology, high-efficiencycountercurrent extraction, microwave drying technology, spray drying and
other advanced production equipment, and has formed an annual output of 200 tons of high-purity plant extracts
production capacity, Complete product specifications and stable quality.With the certificate of ISO9001:14001:45001.

Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Payment by T/T, Western Union or Paypal
Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost

 

How to order

1. Make sure your quantity need and Leave us message, with your mailed details shown: Including
 contact name, address information, contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.