Plant Extract Imperatorin 98% Powder 482-44-0

• Customization: Available
• Certification: RoHS, BRC, ISO, FDA, HACCP
• Assay Method: HPLC
• Model NO.: Imperatorin powder
• Application Form: Injection, Lotion, Suppository, Paste, Tablet, Capsule
• Application: Food, Health Care Products, Medicine, Health-Care Products, Cosmetic Products
• State: Powder
• Extract Source: Radix Angelicae Extract
• Product Name: Imperatorin
• Other Name: Marmelosin
• CAS No: 482-44-0
• Mf: C16h14o4
• Extraction Type: Solvent Extraction
• Part Used: Seed
• Grade: Food Grade, Medical Grade
• Function: Antibacterial, Relieve Pain
• MOQ: 10g
• Sample: Support
• Storage Conditions: Store in a Dry and Dark Place, Sealed
• Shelf Life: 2 Years
• Transport Package: 1.1 Kg Aluminum Foil Bag; 2.10 Kg Carton Packing
• Specification: 98%
• Trademark: HONGKANGBIO
• Origin: China
• HS Code: 1302199099
• Production Capacity: 10000kg/M

Product Description

Plant extract imperatorin 98% powder 482-44-0

Product Name	Angelica dahurica Extract Imperatorin
Exterior	Brown powder(1%), write powder(98%)
Active Ingredient	Imperatorin 1% 98%
Test Method	HPLC
Extraction Solvent	Ethanol/ Water
CAS NO	482-44-0
Molecular Formula	C16H14O4
Molecular Weight	270.27996

The imperatorin extracted from the dried roots of the genus Umbelliferae has been shown to have antibacterial,
antiasthmatic,antiallergic, dilated blood vessels, and inhibition of tumor cell proliferation. Lipid microspheres and
liposomes are drug carriers prepared by using natural lipid materials such as phospholipids and cholesterol.
With this carrier, drugs can be transported to the site of the lesions, and the drug molecules can be protected
from degradation by biological enzymes. The pre-prescription study and drug stability test of imperatorin can
provide a theoretical basis for the design optimization of the injection of imperatorin microspheres. The application
of lipid microsphere technology to the study of imperatorin drugs can reduce the renal side effects of drugs under
the precursors that maintain efficacy.

1-Function:

Effect on the central nervous system
        The effect of imperatorin on seizures was studied using the maximal electroconvulsive epileptic seizure
threshold model in mice. The study found that intraperitoneal injection of 50 and 100 mg/kg-1 of imperatorin
30 minutes earlier could increase the voltage threshold of seizures in mice by 38% and 68%, respectively,
and demonstrated that imperatorin improves mice with electrical stimulation. The effect of the onset threshold
is dose and time dependent.


Effects on the cardiovascular system
      The chromatographic retention peaks of imperatorin and verapamil were similar. It can reduce the protein
content and cell volume of cardiomyocytes prestimulated by angiotensin I, and its effect is dose-dependent: the
ratio of heart weight of spontaneously hypertensive rats treated with angiotensin I is significantly reduced,
indicating that the effect of angiotensin I on both in vivo and in vitro is anti-hypertrophy.


Antibacterial and antiviral activity
      Imperatorin has significant antibacterial and antiviral activity. Seven components were extracted from the
flowers of Magydaris tomcntosa, and four components, including eucrutin, were tested for bacteriostasis. It was
found that eucrutin had strong inhibitory activity against both gram-positive and gram-negative bacteria (minimum
bacteriostasis concentration was 32-128 mg-ml).
 

2-Application

Medicine and Health care product
        Dahuricae dahuricae root as medicine (the main components of imperatorin, isoimperatorin), has the functions
of dispelling diseases, dehumidifying, discharging pus, promoting blood circulation and relieving pain. Cure cold,
headache, rhinitis, toothache. Red white belt, pain furuncle swelling poison and other diseases, can also be used as
spices and medicinal wine.

Shaanxi Hongkang Biological Technology Co., Ltd was founded in 2010, professional committed to the
natural plant active ingredient research, development, production and sales, with own import and export rights.
Widely used in cosmetics, health products, food additives and other industries. Shaanxi Hongkang will
continuously to focus on and serve human health from a global perspective, and create high-quality products
in the field of green health.

After years of continuous development, company has been accumulated rich experience in international trade
and customer resources, established a stable customer base and perfect marketing service network.Company
has perfect quality assurance system, implement strict quality control standards.

The quality management department is equipped with a number of sets of UV, GC,HPLC, GC-MS and other
advanced testing and experimental instruments.Besides, it has a detailed division of labor for the three functions
of process research, quality assurance and quality inspection, which can effectively and comprehensively control
the quality of the production process, conduct comprehensive inspection and analysis on the final product, and
ensure the quality of the product.

Providing users with satisfactory products is our constant pursuit. the company has several plant extraction
production lines in the workshop,And supercritical CO2 extraction,column separation technology, membrane
separation technology, high-efficiencycountercurrent extraction, microwave drying technology, spray drying and
other advanced production equipment, and has formed an annual output of 200 tons of high-purity plant extracts
production capacity, Complete product specifications and stable quality.With the certificate of ISO9001:14001:45001.

Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples. Or if you have special requirement on the goods, we can prepare 
samples according to your requirement and send to you for your confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can 
either pay us the shipping cost or arrange a courier to collect the samples.

Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g. For other low value product, 
our MOQ starts from 100g and 1kg.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.

Q5: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by 
Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation., then you can make 
payment accordingly.

Q6: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to 
customer. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your 
payment immediately.
 

How to order? 
1. Make sure your quantity need and Leave us message, with your mailed details shown: Including contact name,
    address information, contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.